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Polyarticular Juvenile Idiopathic Arthritis (JIA)

Basic facts about JIA

JIA

Juvenile idiopathic arthritis (JIA) is a general term covering all categories of chronic inflammatory joint diseases starting before the age of 16 years. JIA occurs when the body's immune system attacks its own cells and tissues. The first signs often appear in the joints and surrounding tissues, and present as joint pain, swelling, and stiffness. Approximately 6,200 (0.10%) Canadians aged 15 years and younger are diagnosed with JIA. Some forms of JIA are more common in girls.

ABRILADA and JIA

ABRILADA is used to treat patients 2 years of age and older with polyarticular juvenile idiopathic arthritis (JIA).

How ABRILADA works

Your immune system works to protect your body from bacteria, viruses, and other foreign agents. In an autoimmune disease like polyarticular JIA, the immune system mistakenly recognizes the body as foreign and attacks healthy body cells.

The way ABRILADA works is by binding to a substance called TNF-alpha (which stands for tumour necrosis factor alpha) and decreasing the inflammation process of JIA. However, ABRILADA can also lower the body’s ability to fight infections, and taking it can make you or your child more prone to getting infections, or make any infection worse.

Taking my ABRILADA

ABRILADA is administered by injection under the skin, also called a subcutaneous injection.

What is the usual dose?

Children 2 years and older

Weighing 10 to <30 kg


1
20 mg
every other week

Weighing 30 kg or more


1
40 mg
every other week
If you miss your dose of ABRILADA, inject the missed dose as soon as you remember, and take the next dose as planned at the next scheduled time.


For more information or to reach your Care Coach

  • For more information or to
  • reach your Care Coach
  • (Monday – Friday,
  • 8:00 AM – 8:00 PM EST)

PP-ABD-CAN-0037-EN