Log out

A

A

A

FR

Hidradenitis Suppurativa (HS)

Basic facts about HS

Hidradenitis suppurativa (HS) is a fairly common chronic skin condition that leads to tender, expanding, inflamed lumps under the skin. HS affects an estimated 1 million Canadians (almost 4 out of every 100 adults) and has been found to more commonly develop in women than men.

ABRILADA and HS

ABRILADA is used to treat adults and adolescents (12–17 years old, weighing ≥30 kg) with moderate to severe hidradenitis suppurativa (HS) who did not respond to antibiotics.

How ABRILADA works

Your immune system works to protect your body from bacteria, viruses, and other foreign agents. In HS, the immune system mistakenly recognizes the body as foreign and attacks healthy body cells.

When you have HS, your immune system overproduces a substance called TNF-alpha (which stands for tumour necrosis factor alpha). The extra TNF-alpha can attack normal healthy body tissues and cause inflammation.

The way ABRILADA works is by binding to TNF-alpha and decreasing the inflammation process of HS. However, ABRILADA can also lower the body’s ability to fight infections, and taking it can make you prone to getting infections, or make any infection worse.

Taking my ABRILADA

ABRILADA is administered by injection under the skin, also called a subcutaneous injection.

What is the usual dose?

1st dose (day 1/week 0)

4
160 mg
•    4 X 40 mg injections 
     in one day, 
or
•   2 X 40 mg 
injections
    per day over two days

2nd dose (Week 2)

2
80 mg
•   2 X 40 mg injections
    in one day

Maintenance period (after 4 weeks)

1
40 mg
every week
If you miss your dose of ABRILADA, inject the missed dose as soon as you remember, and take the next dose as planned at the next scheduled time.

1st dose

2
80 mg
•   2 X 40 mg injections
   in one day

Subsequent doses (after 1 week)

1
40 mg
every other week
(depending on your child’s response, the doctor may increase the dose to 40 mg every week)
If you miss your dose of ABRILADA, inject the missed dose as soon as you remember, and take the next dose as planned at the next scheduled time.


For more information or to reach your Care Coach

  • For more information or to
  • reach your Care Coach
  • (Monday – Friday,
  • 8:00 AM – 8:00 PM EST)

PP-ABD-CAN-0037-EN